SIDIS Prime before V4.0.400 is affected by multiple vulnerabilities in the components OPC UA and OpenSSL, that could allow an unauthenticated attacker with access to the network where SIDIS Prime is installed to reuse OPC UA client credentials, create a denial of service condition of the SIDIS Prime OPC UA client, or create a denial of service condition of the SIDIS Prime TLS service. Siemens has released a new version of SIDIS Prime and recommends to update to the latest version.